Crafted Runes do not occur naturally and can only be crafted in the Alchemy Shop. They cannot be Scavenged, either.
| Small | Medium | Large | Drop Type | Crafting Powder | |||
|---|---|---|---|---|---|---|---|
| Void |  |
 |
 |
Decreases Odds to win Nothing | Black | ||
| Speed |  |
 |
 |
Increases Movement Speed | White & Light Gray | ||
| Max Power |  |
 |
 |
Increases Max Power | Red & Light Gray | ||
| Max Mana |  |
 |
 |
Increases Max Mana | Blue & Light Gray | ||
| Max Energy |  |
 |
 |
Increases Max Energy | Green & Light Gray | ||
| Gambler |  |
 |
 |
Randomly increases Energy, Gem, Gold, Mana, Power and Nothing Odds | Black, White, Light Gray & Dark Gray | ||
| Puzzles |  |
 |
 |
Increase Odds to win Puzzle Pieces | Purple & Light Gray | ||
| Quest Items |  |
 |
 |
Increase Odds to win Quest Items | Yellow & Light Gray | ||
| Shinies |  |
 |
 |
Increase Odds to win Gems and decrease Nothing | Purple, Black & White | ||
| Alchemy |  |
 |
 |
Increase Odds to win Gold and decrease Nothing | Yellow, Black & White | ||
| Mystic |  |
 |
 |
Increase Odds to win Mana and decrease Nothing | Blue, Black & White | ||
| Storm |  |
 |
 |
Increase Odds to win Power and decrease Nothing | Red, Black & White | ||
| Efficiency |  |
 |
 |
Increase Odds to win Energy and decrease Nothing | Green, Black & White | ||
| Mana Void |  |
 |
 |
Replace some Nothing with Mana | Blue, Black & Dark Gray | ||
| Power Void |  |
 |
 |
Replace some Nothing with Power | Red, Black & Dark Gray | ||
| Energy Void |  |
 |
 |
Replace some Nothing with Energy | Green, Black & Dark Gray | ||
| Healthy Eating |  |
 |
 |
Win Gold when you win Energy | Green, Yellow, White & Light Gray Powders | ||
| Grand Mana |  |
 |
 |
Boost Mana Odds | Blue & White | ||
| Grand Power |  |
 |
 |
Boost Power Odds | Red & White | ||
| Grand Gem |  |
 |
 |
Boost Gem Odds | Purple & White | ||
| Grand Energy |  |
 |
 |
Boost Energy Odds | Green & White | ||
| Grand Gold |  |
 |
 |
Boost Gold Odds | Yellow & White | ||